R = –095 in dogs3) • SDMA as an early indicator of CKD A recently published study found that SDMA increased on average 17 months earlier than creatinine in cats with CKD which on average occurred when 40% of GFR was lost1 A similar study in dogs with CKD found thatThe use of a word to convey multiple meanings at the same timeSDMA is a sensitive indicator of kidney function that detects as little as 25% loss of function 1,2 SDMA is more reliable than creatinine as an indicator of kidney function because it is not influenced by confounding conditions 4,5 SDMA is an earlier indicator of progressive kidney function loss, often increasing before other parameters 1–3
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